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Home Antibody All anti-MAPKAPK2 antibodies

Anti-MAPKAPK2 PHOSPHO Antibody EPR992Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303763
  • Rabbit monoclonal antibody against MAPKAP Kinase-2 Phospho (pT334) (EPR992Y )
100ul 325 3-7 Days
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WB(2)
IHC(1)
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Also for MAPKAPK2 (NM_004759)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human MAPKKAP Kinase-2 was used as immunogen.
Clone NameEPR992Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500; IHC: 1:100 - 250; ICC: 1:100 - 250
Predicted MW Explanation 46 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), transcript variant 1
Alternative NameMAPKAP-K2; MK-2; MK2
Database LinkNP_004750
Entrez Gene 9261 Human
FunctionThis gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayVEGF signaling pathwayNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - MAPKAP Kinase 2 (phospho T334) antibody [EPR992Y]; All lanes : Anti-MAPKAP Kinase 2 (phospho T334) antibody [EPR992Y] at 1/500 dilution.Lane 1 : HeLa cell lysate, untreated.Lane 2 : HeLa cell lysate treated with anisomycin.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP labeled at 1/2000 dilution.Predicted band size : 46 kDa.Observed band size : 50 kDa .
WB Image
Western blot - Anti-MAPKAP Kinase 2 (phospho T334) antibody [EPR992Y]; All lanes : Anti-MAPKAP Kinase 2 (phospho T334) antibody [EPR992Y].Lane 1 : HEK293 cells transfected with GFP-MK2 .Lane 2 : HEK293 cells transfected with GFP-MK2 and treated 1h with p38 inhibitor.Lane 3 : HEK293 cells transfected with GFP-T334A MK2.Predicted band size : 46 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - MAPKAP Kinase 2 (phospho T334) antibody [EPR992Y]; Ab51018 (1/100) staining human MAPKAP kinase 2 in human breast carcinoma tissue by immunohistochemistry using paraffin embedded tissue.

 

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