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Home Antibody All anti-BCL10 antibodies

Anti-BCL10 Antibody ep605y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303756
  • Rabbit monoclonal antibody against Bcl-10 (EP605Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418351) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-term of human Bcl-10 was used as immunogen.
Clone Nameep605y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:2000; IHC-P: Use at an assay dependent dilution; FC: 1:20; IP: 1:30
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Whole Cell Lysate
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 10 (BCL10)
Alternative Namec-E10; CARMEN; CIPER; CLAP; mE10
Database LinkNP_003912
FunctionThis gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Bcl10 antibody [ep605y]; Anti-Bcl10 antibody [ep605y] at 1/2000 dilution + Raji cell lysate at 10 ug.Predicted band size : 31 kDa.Observed band size : 32 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Bcl10 antibody [ep605y]; Immunohistochemical analysis of paraffin-embedded human colon carcinoma using TA303756 at a dilution of 1/50.

 

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