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Anti-BCL10 Antibody ep605y
Also for BCL10 (NM_003921)
|A synthetic peptide corresponding to residues near the N-term of human Bcl-10 was used as immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:2000; IHC-P: Use at an assay dependent dilution; FC: 1:20; IP: 1:30
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Whole Cell Lysate (Protein A or G Sepharose)
|Does not react with Mouse, Rat
|Homo sapiens B-cell CLL/lymphoma 10 (BCL10)|
|c-E10; CARMEN; CIPER; CLAP; mE10|
|This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq]. |
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Western blot - Bcl10 antibody [ep605y]; Anti-Bcl10 antibody [ep605y] at 1/2000 dilution + Raji cell lysate at 10 µg.Predicted band size : 31 kDa.Observed band size : 32 kDa .
Immunohistochemistry (Paraffin-embedded sections) - Bcl10 antibody [ep605y]; Immunohistochemical analysis of paraffin-embedded human colon carcinoma using ab40752 at a dilution of 1/50.