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Anti-IRS2 Antibody EP903Y
Also for IRS2 (NM_003749)
|A synthetic peptide corresponding to residues near the N-terminus of human IRS-2 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:100,000; IHC: 1:50-100; ICC: 1:250 100; IP: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Does not react with Mouse, Rat
|Homo sapiens insulin receptor substrate 2 (IRS2)|
|This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq]. |
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Western blot - IRS2 antibody [EP903Y]; Anti-IRS2 antibody [EP903Y] at 1/100000 dilution + 293 cell lysate at 10ug/lane, plus insulin .Secondary.Goat-anti rabbit, HRP labelled, at 1/2000 dilution.Predicted band size : 137 kDa.Observed band size : 160 kDa .Additional bands at : 50 kDa (possible non-specific binding).
Immunohistochemistry (Paraffin-embedded sections) - IRS2 antibody [EP903Y]; This image shows human cervical carcinoma stained with ab46811 at 1/50 dilution.