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Home Antibody All anti-ZAP70 antibodies

Anti-ZAP70 Antibody E267

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303737
  • Rabbit monoclonal antibody against ZAP-70(E267)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC421504) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for ZAP70 (NM_001079)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in N-terminus of human ZAP-70 was used as immunogen.
Clone NameE267 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsFC: 1:40; WB: 1:500; IP: 1:30
Predicted MW Explanation 70 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Is unsuitable for ICC or IHC.

Reference Data

Target NameHomo sapiens zeta-chain (TCR) associated protein kinase 70kDa (ZAP70), transcript variant 1
Alternative NameSRK; STCD; STD; TZK; ZAP-70
Database LinkNP_001070
Entrez Gene 7535 Human
Entrez Gene 22637 Mouse
Entrez Gene 301348 Rat
FunctionThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome Natural killer cell mediated cytotoxicityT cell receptor signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ZAP70 antibody [E267]; Anti-ZAP70 antibody [E267] at 1/500 dilution + Jurkat cell lysates.Predicted band size : 70 kDa.Observed band size : 70 kDa.

 

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