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Home Antibody All anti-TYK2 antibodies

Anti-TYK2 Antibody EP1127Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303726
  • Rabbit monoclonal antibody against Tyk2(EP1127Y)
100ul 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human Tyk2 was used as an immunogen.
Clone NameEP1127Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50000; IP: 1:50; ICC/IF: 1:100 - 1:250; IHC-P: Use at an assay dependent dilution
Predicted MW Explanation 134 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens tyrosine kinase 2 (TYK2)
Alternative NameIMD35; JTK1
Database LinkNP_003322
Entrez Gene 7297 Human
Entrez Gene 54721 Mouse
Entrez Gene 100361294 Rat
FunctionThis gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - TYK2 antibody [EP1127Y]; Anti-TYK2 antibody [EP1127Y] at 1/50000 dilution + Raji cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 134 kDa.Observed band size : 140 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - TYK2 antibody [EP1127Y]; TA303726 (1/100) staining TYK2 in paraffin embedded human liver tissue by Immunohistochemistry.

 

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