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Anti-TNNI3 Antibody EP1106Y
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Also for TNNI3 (NM_000363)
|A synthetic peptide corresponding to residues near the N-terminus of human Troponin 1 was used as an immunogen.|
||WB: 1:1,000,000; IHC: 1:250 500; IP: 1:50
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens troponin I type 3 (cardiac) (TNNI3)|
|CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1|
|Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq]. |
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Western blot analysis on fetal heart cell lysate using anti-Troponin RabMAb (TA303719), dilution 1:1,000,000
Immunohistochemical staining of paraffin-embedded human cardiac muscle using anti-Troponin RabMAb (TA303719).