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Anti-STAT6 Antibody E265

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IF(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in C-terminus of human Stat-6 was used as immunogen. The antibody does not cross-react with other Stat family members.
Clone Name	E265	Isotype	Rabbit IgG
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IF	Suggested Dilutions	WB: 1:500 - 5000; ICC: 1:250-500; FC: 1:10; IP: 1:30
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2
Alternative Name	D12S1644; IL-4-STAT; STAT6B; STAT6C
Database Link	NP_003144
Function	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq].
Related Pathway	Adipogenesis Jak-STAT signaling pathway

Related Lysate from OriGene • Transient overexpression lysate of signal transducer and activator of transcription 6, interleukin-4 induced (STAT6) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • STAT6 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • STAT6 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Stat6 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • STAT6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Stat6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 , Myc-DDK-tagged • Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2, mGFP tagged Related cDNA Clones • Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)