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Anti-STAT6 Antibody E265
Also for STAT6 (NM_003153)
|A synthetic peptide corresponding to residues in C-terminus of human Stat-6 was used as immunogen. The antibody does not cross-react with other Stat family members.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:500 - 5000; ICC: 1:250-500; FC: 1:10; IP: 1:30
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2|
|D12S1644; IL-4-STAT; STAT6B; STAT6C|
|The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq]. |
Jak-STAT signaling pathway
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Western blot - STAT6 antibody [E265]; Anti-STAT6 antibody [E265] at 1/5000 dilution.Predicted band size : 94 kDa.Observed band size : 100 kDa .
Immunofluorescence - STAT6 antibody [E265]; Immunofluorescent staining of HeLa cells using TA303709