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Home Antibody All anti-STAT6 antibodies

Anti-STAT6 Antibody E265

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303709
  • Rabbit monoclonal antibody against Stat-6(E265)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401100) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for STAT6 (NM_003153)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in C-terminus of human Stat-6 was used as immunogen. The antibody does not cross-react with other Stat family members.
Clone NameE265 IsotypeRabbit IgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:500 - 5000; ICC: 1:250-500; FC: 1:10; IP: 1:30
Predicted MW Explanation 100kDa
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2
Alternative NameD12S1644; IL-4-STAT; STAT6B; STAT6C
Database LinkNP_003144
Entrez Gene 6778 Human
FunctionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq].
Related PathwayStem cell relevant signaling - DSL/Notch pathwayStem cell relevant signaling - JAK/STAT signaling pathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - STAT6 antibody [E265]; Anti-STAT6 antibody [E265] at 1/5000 dilution.Predicted band size : 94 kDa.Observed band size : 100 kDa .
IF Image
Immunofluorescence - STAT6 antibody [E265]; Immunofluorescent staining of HeLa cells using TA303709

 

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