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Anti-STAT2 Antibody Y141
Also for STAT2 (NM_005419)
|A synthetic peptide corresponding to residues near N-terminus of human Stat-2 was used as immunogen. This antibody detects both long and short forms of Stat-2.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:5000 - 1:10000; ICC: 1:50 - 1:100; IHC-P: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1|
|ISGF-3; P113; STAT113|
Entrez Gene 6773 Human
Entrez Gene 20847 Mouse
Entrez Gene 288774 Rat
|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq]. |
|Transcription FactorsDruggable Genome Chemokine signaling pathwayJak-STAT signaling pathway|
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Western blot - STAT2 antibody [Y141]; Anti-STAT2 antibody [Y141] at 1/500 dilution + K562 cell lysate.Predicted band size : 98 kDa.Observed band size : 100 kDa .
Immunohistochemistry (Paraffin-embedded sections) - STAT2 antibody [Y141]; Immunohistochemical analysis of paraffin-embedded human thyroid cancer using TA303708