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Anti-STAT2 Antibody Y141
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Also for STAT2 (NM_005419)
|A synthetic peptide corresponding to residues near N-terminus of human Stat-2 was used as immunogen. This antibody detects both long and short forms of Stat-2.|
||WB: 1:500; IHC: 1:100-250; ICC: 1:50-100
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1|
|ISGF-3; P113; STAT113|
|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq]. |
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
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Western blot analysis on K562 cell lysate using anti-Stat-2 RabMAb (TA303708), dilution 1:500.
Immunohistochemical analysis of paraffin-embedded human thyroid cancer using anti-Stat-2 RabMAb (TA303708).