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Anti-PRKDC Antibody Y393

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

IF(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in the C-term of human DNA-PK was used as immunogen. This antibody may detect splice isoform 2 according to sequence analysis.
Clone Name	Y393	Isotype	Rabbit IgG
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB: 1:1,000; IHC: 1:50; ICC: 1:250-500
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1
Alternative Name	DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; p350; XRCC7
Database Link	NP_008835
Function	The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM].
Related Pathway	Cell cycle

Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • PRKDC - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • PRKDC - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Prkdc - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • PRKDC - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Prkdc - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1 as transfection-ready DNA • PRKDC Mutant (L3062R), Myc-DDK-tagged ORF clone of Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1 as transfection-ready DNA Related cDNA Clones • Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)