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Home Antibody All anti-PRKDC antibodies

Anti-PRKDC Antibody Y393

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SKU Description Amount Price Availability*  
TA303663 Rabbit monoclonal antibody against PRKDC / DNA-PK (Y393) 100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-term of human DNA-PK was used as immunogen. This antibody may detect splice isoform 2 according to sequence analysis.
Clone NameY393 IsotypeIgG
Species ReactivityMouse, Rat, Human, Armenian Hamster ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application * Suggested DilutionsWB: 1:1,000; IHC: 1:50; ICC: 1:250-500
Predicted MW Explanation 469 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Reference Data

Target NameHomo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1
Alternative NameDNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7
Database LinkNP_008835
Entrez Gene 5591 Human
Entrez Gene 19090 Mouse
Entrez Gene 360748 Rat
FunctionThe PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM].
Related PathwayProtein KinaseDruggable Genome Non-homologous end-joiningCell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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