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Home All anti-PRKCA antibodies
Anti-PRKCA Phospho Antibody EP2608Y
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for PRKCA (NM_002737)
OriGene Data
| A phospho specific peptide corresponding to residues surrounding threonine 497 of human PKC alpha was used as an immunogen. This antibody detects PKC alpha phosphorylated on thr497. |
| EP2608Y |
Rabbit IgG |
| Human, Mouse, Rat |
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| WB, IHC, IF |
WB: 1:50,000 -100,000; IHC: 1:100 -250; ICC: 1:100 -250; IP: 1:50 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens protein kinase C, alpha (PRKCA) |
| AAG6; PKC-alpha; PKCA; PRKACA |
| NP_002728 |
| Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq]. |
EGFR1 Signaling Pathway Focal Adhesion Hemostasis MAPK signaling pathway Melanogenesis Wnt Signaling Pathway |
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* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on Jurkat cell lysates using anti-Phospho-PKCalpha (pT497) RabMAb (TA303660), 1:100,000 dilution. Cells were either (A) untreated (B) treated with LP
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidneys using anti-PKCa RabMAb (TA303660)
IF Image
Immunofluorescent staining of HeLa cells using anti-PKCa RabMAb (TA303660).
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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