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Home Antibody All anti-PLCG1 antibodies

Anti-PLCG1 Antibody EP1898-7Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303644 Rabbit monoclonal antibody against PLC y-1(EP1898-7Y ) 100ul $325 In Stock
LC419181 PLCG1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for PLCG1 (NM_002660)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Tyrosine 783 was used as an immungen.
Clone NameEP1898-7Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:5000 - 1:10000; IP: 1:50; ICC: 1:250 - 1:500
Predicted MW Explanation 149 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens phospholipase C, gamma 1 (PLCG1), transcript variant 1
Alternative NameNCKAP3; PLC-II; PLC1; PLC148; PLCgamma1
Database LinkNP_002651
Entrez Gene 5335 Human
Entrez Gene 18803 Mouse
Entrez Gene 25738 Rat
FunctionThe protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Inositol phosphate metabolismMetabolic pathwaysErbB signaling pathwayCalcium signaling pathwayPhosphatidylinositol signaling systemVEGF signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Phospholipase C gamma 1 antibody [EP1898-7Y]; Anti-Phospholipase C gamma 1 antibody [EP1898-7Y] at 1/10000 dilution + Jurkat cell lysates at 10 ug.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 149 kDa.Observed band size : 149 kDa.


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