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Anti-PLCG1 Antibody EP1898-7Y
Also for PLCG1 (NM_002660)
|A synthetic peptide corresponding to residues surrounding Tyrosine 783 was used as an immungen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:5000 - 1:10000; IP: 1:50; ICC: 1:250 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens phospholipase C, gamma 1 (PLCG1), transcript variant 1|
|NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1|
|The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
EGFR1 Signaling Pathway
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Western blot - Phospholipase C gamma 1 antibody [EP1898-7Y]; Anti-Phospholipase C gamma 1 antibody [EP1898-7Y] at 1/10000 dilution + Jurkat cell lysates at 10 µg.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 149 kDa.Observed band size : 149 kDa.