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Home Antibody All anti-PIK3CG antibodies

Anti-PIK3CG Antibody Y388

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303640
  • Rabbit monoclonal antibody against PI3-kinase p110 subunit gamma, N-term(Y388)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419184) , 20ug Explanation
100ul $325 3-7 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
FC(1)
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Also for PIK3CG (NM_002649)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide of in the N-term of human PI3-K p110 gamma was used as an immunogen.
Clone NameY388 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1,000; FC: 1:50; IP: 1:50
Predicted MW Explanation 126 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (PIK3CG), transcript variant 1
Alternative Namep110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
Database LinkNP_002640
Entrez Gene 5294 Human
FunctionThis gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq].
Related PathwayES Cell Differentiation/IPSDruggable Genome Inositol phosphate metabolismErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - PI 3 Kinase catalytic subunit gamma antibody [Y388]; Anti-PI 3 Kinase catalytic subunit gamma antibody [Y388] at 1/1000 dilution + Jurkat cell lysate.Predicted band size : 126 kDa.Observed band size : 110 kDa .
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Flow Cytometry - Anti-PI 3 Kinase catalytic subunit gamma antibody [Y388]; Overlay histogram showing HeLa cells stained with TA303640 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody for 30 min at 22°C. The secondary antibody used was Alexa Fluor 488 goat anti-rabbit IgG (H&L) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1ug/1x10^6 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.
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