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Anti-PAK1 Antibody EP709Y

WB(1)

IHC(1)

IF(1)

Gene Name Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 2 Synonyms: PAKalpha Immunogen A synthetic peptide corresponding to residues in the human PAK1 protein was used as immunogen. Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Clone Name EP709Y Isotype Rabbit IgG Species Reactivity Human, Mouse, Rat Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IHC, IF Suggested Dilutions WB: 1:10,000-50,000; IHC: 1: 250-500; ICC: 1:250-500; IP: 1:50 Background PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Related Pathway EGFR1 Signaling Pathway Focal Adhesion MAPK signaling pathway

Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • PAK1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • PAK1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Pak1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • PAK1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Pak1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 2 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 2 as transfection-ready DNA Related cDNA Clones • Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 2 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)