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Home Antibody All anti-NPM1 antibodies

Anti-NPM1 Antibody EP1848Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303620
  • Rabbit monoclonal antibody against NPM (N-term) (EP1848Y )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC421985) , 20ug
100ul $325 In Stock
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WB(1)
IHC(4)
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Also for NPM1 (NM_001037738)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the N-terminus of human NPM was used as an immunogen
Clone NameEP1848Y IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:200,000; IHC: 1:100 - 250; FC: 1:40; IP: 1:60
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 3
Alternative NameB23; NPM
Database LinkNP_001032827
FunctionNPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM].
Related Pathway

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WB Image
Western blot - Nucleophosmin antibody [not given on sds]; Anti-Nucleophosmin antibody [EP1848Y] at 1/200000 dilution + Hela cell lysate at 10 µg.Secondary.Goat anti-rabbit HRP labeled at 1/2000 dilution.Predicted band size : 33 kDa.Observed band size : 35 & 38 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Nucleophosmin antibody [not given on sds]; Immunohistochemical staining of paraffin-embedded non-Hodgkin?? lymphoma using TA303620 at a 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Nucleophosmin antibody [EP1848Y](TA303620); TA303620 showing positive staining in Breast carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Nucleophosmin antibody [EP1848Y](TA303620); TA303620 showing positive staining in Cervical carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Nucleophosmin antibody [EP1848Y](TA303620); TA303620 showing positive staining in Glioma tissue.

 

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