OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-MYC antibodies

Anti-MYC PHOSPHO Antibody E203

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303607 Rabbit monoclonal antibody against Phospho-c-Myc (pT58/S62)(E203) (phospho-specific) 100ul $325 In Stock
Add to Shopping Cart

spacer
WB(1)
IF(1)
FC(1)

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Thr58 and Ser62 of human C-Myc was used as immunogen. The antibody only detects c-Myc phosphorylated on Threonine 58 and Serine 62. Predicted to cross-react with most species, based on sequ
Clone NameE203 IsotypeRabbit IgG
Species ReactivityRat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF, FC Suggested DilutionsWB: 1:1,000; ICC: 1:50-100; IP: 1:100
Predicted MW Explanation 49kDa (Detect a band at 57kDa)
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC)
Alternative NamebHLHe39; c-Myc; MRTL; MYCC
Database LinkNP_002458
Entrez Gene 4609 Human
Entrez Gene 24577 Rat
FunctionThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq].
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - TGFb/BMP signaling pathwayStem cell relevant signaling - Wnt Signaling pathwayStem cell - PluripotencyEmbryonic stem cellsInduced pluripotent stem cellsTranscription FactorsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCell cycleWnt signaling pathwayTGF-beta signaling pathwayJak-STAT signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - c-Myc (phospho T58 + S62) antibody [E203]; All lanes : Anti-c-Myc (phospho T58 + S62) antibody [E203] at 1/1000 dilution.Lane 1 : Untreated A431 cell lysate.Lane 2 : TPA treated A431 cell lysate.Predicted band size : 49 kDa.Observed band size : 57 kDa .
spacer
Immunofluorescence - c-Myc (phospho T58 + S62) antibody [E203]; Immunofluorescent staining of A431 cells
spacer
Flow Cytometry - Anti-c-Myc (phospho T58 + S62) antibody; Overlay histogram showing Jurkat cells stained with TA303607 (red line). The secondary antibody used was Alexa Fluor 488 goat anti-rabbit IgG (H&L) at 1:2000. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1ug/1x10^6 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title