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Home All anti-MYC antibodies
Anti-MYC Phospho Antibody E203
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
OriGene Data
| A synthetic phospho-peptide corresponding to residues surrounding Thr58 and Ser62 of human C-Myc was used as immunogen. The antibody only detects c-Myc phosphorylated on Threonine 58 and Serine 62. Predicted to cross-react with most species, based on sequ |
| E203 |
Rabbit IgG |
| Human, Mouse |
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| WB, IF |
WB: 1:1,000; ICC: 1:50-100; IP: 1:100 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens v-myc myelocytomatosis viral oncogene homolog (avian) (MYC) |
| bHLHe39; c-Myc; MRTL |
| NP_002458 |
| The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]. |
Apoptosis Cell cycle EGFR1 Signaling Pathway Jak-STAT signaling pathway MAPK signaling pathway TGF Beta Signaling Pathway Wnt Signaling Pathway |
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* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on A431 cell lysate using anti-Phospho-c-Myc (pT58/pS62) RabMAb (TA303607), dilution 1:1,000. Cell lysates were either (1) untreated or (2) treated with TPA.
IF Image
Immunofluorescent staining of A4321 cells using anti-phospho-c-Myc (T58/S62) RabMAbb (TA303607).
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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