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Anti-MMP17 Antibody EP1270Y
Also for MMP17 (NM_016155)
|A synthetic peptide corresponding to residues on human MMP-17 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:1000; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:50 - 1:100; IHC-FoFr: Use at an assay dependent concentration
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens matrix metallopeptidase 17 (membrane-inserted) (MMP17)|
|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. |
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Western blot - MMP17 antibody [EP1270Y]; Anti-MMP17 antibody [EP1270Y] at 1/1000 dilution + Mouse brain lysate at 10 µg.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 67 kDa.Observed band size : 58 kDa .
Immunohistochemistry (Paraffin-embedded sections) - MMP17 antibody [EP1270Y]; Ab51075 (1:50) staining human MMP17 in human lymphoma tissue by immunohistochemistry using paraffin embedded tissue.
Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-MMP17 antibody [EP1270Y]; Immunohistochemical analysis of rat basolateral amygdala tissue, staining MMP17 with TA303604. Tissue was permeabilized with 0.5% Triton-X 100 before incubating with primary antibody (1/100) for 48 hours at 4Â°C. An AlexaFluor?568 goat anti-rabbit IgG was used as the secondary antibody.
Immunocytochemistry/ Immunofluorescence - MMP17 antibody [EP1270Y]; Immunofluorescent staining of HeLa cells using TA303604 (1:50).