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Anti-MMP9 Antibody EP1328Y
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Also for MMP9 (NM_004994)
|A synthetic peptide corresponding to residues near the N-terminus of human MMP-9 propeptide was used as an immunogen.|
||WB: 1:1000; IHC: 1:50; FC: 1:15
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (MMP9)|
|CLG4B; GELB; MANDP2; MMP-9|
|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq]. |
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Western blot analysis on 5 ng of recombinant protein using anti-MMP-9 propeptide RabMAb (TA303602), dilution 1:1000.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-MMP9 RabMAb (TA303602).