OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-MAP3K11 antibodies

Anti-MAP3K11 Antibody EP1460Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303597
  • Rabbit monoclonal antibody against MLK-3 (C-term) (EP1460Y )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419338) , 20ug Explanation
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IF(1)
spacer
Also for MAP3K11 (NM_002419)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human MLK-3 was used as an immunogen
Clone NameEP1460Y IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsFC: 1:15; WB: 1:5000; ICC/IF: 1:100 - 1:250
BufferDoes not react with Rat. Is unsuitable for IHC-Fr,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC-Fr,IHC-P or IP.

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase kinase kinase 11 (MAP3K11)
Alternative NameMEKK11; MLK-3; MLK3; PTK1; SPRK
Database LinkNP_002410
Entrez Gene 4296 Human
Entrez Gene 26403 Mouse
FunctionThe protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq].
Related Pathway
MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - MLK3 antibody [EP1460Y]; Anti-MLK3 antibody [EP1460Y] - Carboxyterminal end at 1/5000 dilution + A431 cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 93 kDa.Observed band size : 100 kDa .
IF Image
Immunocytochemistry/ Immunofluorescence - MLK3 antibody [EP1460Y]; Immunofluorescent staining of HeLa cells using TA303597 (1:100).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title