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Anti-MAP3K11 Antibody EP1460Y
Also for MAP3K11 (NM_002419)
|A synthetic peptide corresponding to residues on the C-terminus of human MLK-3 was used as an immunogen|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||FC: 1:15; WB: 1:5000; ICC/IF: 1:100 - 1:250
|Does not react with Rat. Is unsuitable for IHC-Fr,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for IHC-Fr,IHC-P or IP.
|Homo sapiens mitogen-activated protein kinase kinase kinase 11 (MAP3K11)|
|MEKK11; MLK-3; MLK3; PTK1; SPRK|
|The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq]. |
MAPK signaling pathway
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Western blot - MLK3 antibody [EP1460Y]; Anti-MLK3 antibody [EP1460Y] - Carboxyterminal end at 1/5000 dilution + A431 cell lysate at 10 µg.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 93 kDa.Observed band size : 100 kDa .
Immunocytochemistry/ Immunofluorescence - MLK3 antibody [EP1460Y]; Immunofluorescent staining of HeLa cells using ab51068 (1:100).