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Anti-KRT6A Antibody EPR1603Y
Also for KRT6A (NM_005554)
|A synthetic peptide corresponding to residues on the C-terminus of human CK-6A was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:100000; ICC: 1:100 - 1:250; IHC-P: Use at an assay dependent concentration
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens keratin 6A (KRT6A)|
|CK6A; CK6C; CK6D; K6A; K6C; K6D; KRT6C; KRT6D; PC3|
|The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]. |
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Western blot - Cytokeratin 6 antibody [EPR1603Y]; Anti-Cytokeratin 6 antibody [EPR1603Y] at 1/100000 dilution + A431 cell lysate at 10 µg.Secondary.Goat anti-rabbit HRP antibody at 1/2000 dilution.Predicted band size : 60 kDa.Observed band size : 60 kDa.
Immunohistochemistry (Paraffin-embedded sections) - Cytokeratin 6 antibody [EPR1603Y]; Ab52620 at 1/100-1/250 dilution staining human squamous cervical carcinoma; paraffin embedded.
Immunocytochemistry/ Immunofluorescence - Cytokeratin 6 antibody [EPR1603Y]; Ab52620 at 1/100-1/250 dilution staining A431 cells.