Homo sapiens kinesin family member 22 (KIF22), transcript variant 1
Synonyms:
A-328A3.2; KID; KNSL4; OBP; OBP-1; OBP-2; SEMDJL2
Immunogen
A phospho-specific peptide corresponding to residues surrounding Serine 427 of human KID was used as an immunogen. This antibody only detects KID phosphorylated on Serine 427.
Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. [provided by RefSeq].
Related Pathway
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Western blot analysis on HeLa cell lysates using anti-Phospho-KID (pS427) RabMAb (TA303566), 1:2000 dilution. Cells were either (A) untreated (B) treated with aphidicolin + nocodazole
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