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Anti-KCND2 Antibody EP982Y
Also for KCND2 (NM_012281)
|A synthetic peptide corresponding to residues near the C-terminus of human Kv4.2 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000; IHC-P: Use at an assay dependent dilution; FC: 1:30
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for ICC or IP.
|Homo sapiens potassium voltage-gated channel, Shal-related subfamily, member 2 (KCND2)|
|Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq]. |
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Western blot - Kv4.2 antibody [EP982Y]; Anti-Kv4.2 antibody [EP982Y] at 1/1000 dilution + Human brain lysate at 10 µg.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Observed band size : 80 kDa .Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.
Immunohistochemistry (Paraffin-embedded sections) - Kv4.2 antibody [EP982Y]; Immunohistochemical staining of paraffin-embedded human brain using Kv4.2 antibody [EP982Y].