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Anti-JAK3 Antibody EP909Y
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Also for JAK3 (NM_000215)
|A synthetic peptide corresponding to residues on the C-terminus of human JAK3 was used as an immunogen.|
||WB: 1:2000; FC: 1:30; IP: 1:50
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens Janus kinase 3 (JAK3)|
|JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK|
|The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq]. |
Jak-STAT signaling pathway
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Western blot analysis on TF-1 cell lysate using anti-JAK3 RabMAb (TA303561), dilution 1:2000