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Anti-JAK3 Antibody Polyclonal

WB(1)

Gene Name Homo sapiens Janus kinase 3 (JAK3) Synonyms: JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK Immunogen A synthetic peptide corresponding to the C-terminal residues of human Jak3 was used as an immunogen. Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Clone Name Polyclonal Isotype Rabbit IgG Species Reactivity Human, Mouse Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB Suggested Dilutions WB: 1:2000 Background The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq]. Related Pathway Jak-STAT signaling pathway

Related Lysate from OriGene • Transient overexpression lysate of Janus kinase 3 (JAK3) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • JAK3 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • JAK3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Jak3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • JAK3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Jak3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens Janus kinase 3 (JAK3) as transfection-ready DNA • Lenti ORF clone of Human Janus kinase 3 (JAK3) , Myc-DDK-tagged • GFP-tagged ORF clone of Homo sapiens Janus kinase 3 (JAK3) as transfection-ready DNA • Lenti ORF clone of Human Janus kinase 3 (JAK3), mGFP tagged • Myc-DDK-tagged ORF clone of Homo sapiens Janus kinase 3 (JAK3) as 200 ug transfection-ready DNA Related cDNA Clones • ORIGENE UNIQUE VARIANT 1 of Homo sapiens Janus kinase 3 (JAK3) as transfection-ready DNA • Homo sapiens Janus kinase 3 (JAK3) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)