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Home Antibody All anti-ITGAX antibodies

Anti-ITGAX Antibody EP1347Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303556
  • Rabbit monoclonal antibody against ITAX (C-term) (EP1347Y )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424468) , 20ug
100ul 325 In Stock
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WB(1)
IHC(7)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human ITAX was used as an immunogen.
Clone NameEP1347Y IsotypeRabbit IgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50,000 100,000; IHC: 1:100 250; ICC: 1:50 100; IP: 1:80
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), transcript variant 2
Alternative NameCD11C; SLEB6
Database LinkNP_000878
FunctionThis gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq].
Related Pathway
Focal Adhesion
Hemostasis

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WB Image
Anti-CD11c antibody [EP1347Y] (TA303556) at 1/1000 dilution + THP-1 + TPA lysate at 10 µg. Secondary: goat anti-rabbit HRP at 1/2000 dilution
IHC Image
Human paraffin-embedded lymph node stained with TA303556 at 1/100 - 1/250 dilution
IHC Image
TA303556 at 1/400 dilution staining CD11c in human tonsil tissue by immunohistochemistry (formalin/PFA-fixed paraffin-embedded sections). Sections were paraformaldehyde fixed, prior to blocking in 10% BSA in FCS (20ml) + DMEM (80ml) for 30 minutes at 21°C and then incubated with TA303556 for 20 hours at 4°C. A biotin conjugated rabbit polyclonal to mouse Ig, diluted 1/400, was used as the secondary antibody.
IHC Image
TA303556 showing positive staining in Normal tonsil tissue.
IHC Image
TA303556 showing negative staining in Normal brain tissue.
IHC Image
TA303556 showing negative staining in Normal breast tissue.
IHC Image
TA303556 showing negative staining in Skeletal muscle tissue.
IHC Image
TA303556 showing positive staining in Normal spleen tissue.

 

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