The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene. [provided by RefSeq].
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Western blot analysis of (A) untreated and (B) AP treated HeLa cell lysates using anti-phospho-HSF1 (pS303/307) RabMAb (TA303541) 1:50,000 dilution. Pan Control: Western blot analysis of (C) untreated and (b) AP treated HeLa cell lysates using anti-H