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Anti-UBE2K Antibody EP1144Y
Also for UBE2K (NM_005339)
|A synthetic peptide corresponding to residues on the N-terminus of human UBC-1 was used as an immunogen|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:500; ICC: 1:100; IP: 1:20
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Does not react with Mouse, Rat
|Homo sapiens ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 1|
|E2-25K; HIP2; HYPG; LIG; UBC1|
|The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]. |
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Western blot - HIP2 antibody [EP1144Y]; All lanes : Anti-HIP2 antibody [EP1144Y] at 1/500 dilution.Lane 1 : Daudi cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : human brain cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 22 kDa.Observed band size : 25 kDa .