OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-GAD2 antibodies

Anti-GAD2 Antibody EPR2553Y

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303520
  • Rabbit monoclonal antibody against GAD2 (EPR2553Y )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424506) , 20ug Explanation
100ul $325 3-7 Days
Add to Shopping Cart
spacer
WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GAD2 was used as an immunogen.
Clone NameEPR2553Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500 - 1:2000
Predicted MW Explanation 65 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 1
Alternative NameGAD65
Database LinkNP_000809
Entrez Gene 2572 Human
Entrez Gene 14417 Mouse
Entrez Gene 24380 Rat
FunctionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq].
Related PathwayDruggable Genome Alanine, aspartate and glutamate metabolismbeta-Alanine metabolismTaurine and hypotaurine metabolismButanoate metabolismMetabolic pathwaysType I diabetes mellitusMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - GAD65 antibody [EPR2553Y]; All lanes : Anti-GAD65 antibody [EPR2553Y] at 1/1000 dilution.Lane 1 : Fetal brain lysate.Lane 2 : Mouse brain lysate.Lane 3 : Rat brain lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 65 kDa.Observed band size : 70 kDa .Additional bands at : 80 kDa. We are unsure as to the identity of these extra bands.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title