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Home Antibody All anti-PTK2B antibodies

Anti-PTK2B Antibody EP206Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303509
  • Rabbit monoclonal antibody against FAK2 / CAKb (C-term) (EP206Y )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC406631) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for PTK2B (NM_173174)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human FAK2 was used as an immunogen.
Clone NameEP206Y IsotypeTissue culture supernatant
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:2000; IHC-P: 1:100 - 1:250; IP: 1:50
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt or ICC/IF.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or ICC/IF.

Reference Data

Target NameHomo sapiens protein tyrosine kinase 2 beta (PTK2B), transcript variant 1
Alternative NameCADTK; CAKB; FADK2; FAK2; PKB; PTK; PYK2; RAFTK
Database LinkNP_775266
FunctionThis gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway
EGFR1 Signaling Pathway

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WB Image
Western blot - PYK2 antibody [EP206Y]; All lanes : Anti-PYK2 antibody [EP206Y] at 1/2000 dilution.Lane 1 : Human brain lysate.Lane 2 : Rat brain lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 116 kDa.Observed band size : 116 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PYK2 antibody [EP206Y]; Immunohistochemical analysis of paraffin-embedded human brain using TA303509 at 1/100 dilution.

 

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