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Anti-EGFR Phospho Antibody EP38Y
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Also for EGFR (NM_201283)
|A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGF receptor was used as immunogen. The antibody detects both EGFR phosphorylated on Tyrosine 1068 of the mature human isoform 1 (corresponding to Y1092 from the precursor|
|Human, Mouse, Rat
||WB: 1:100,000; IHC: 1:100 250; ICC: 1:250 500; IP: 1:50
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 3|
|ERBB; ERBB1; HER1; mENA; PIG61|
|The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]. |
Cytokine-cytokine receptor interaction
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
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Western blot analysis on HeLa cell lysate using anti-EGFR RabMAb (TA303488), dilution 1:100,000
Immunohistochemical staining of paraffin-embedded human lymph node metastasis using anti-EGFR RabMAb (TA303488).