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Home Antibody All anti-EGFR antibodies

Anti-EGFR Antibody E234

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303487
  • Rabbit monoclonal antibody against EGFR (N-term) (E234 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC404515) , 20ug Explanation
100ul 325 In Stock
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WB(1)
FC(1)
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Also for EGFR (NM_201283)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain near N-terminus of human EGFR was used as immunogen. The antibody does not cross-react with other ERBB family members. Predicted to cross-react with rat, pig and bovine, based on se
Clone NameE234 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:500; FC: 1:50
Predicted MW Explanation 180 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Is unsuitable for ICC,IHC or IP.

Reference Data

Target NameHomo sapiens epidermal growth factor receptor (EGFR), transcript variant 3
Alternative NameERBB; ERBB1; HER1; mENA; PIG61
Database LinkNP_958440
Entrez Gene 1956 Human
FunctionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq].
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayProtein KinaseSecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionEndocytosisDorso-ventral axis formationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - EGFR antibody [E234]; Anti-EGFR antibody [E234] at 1/500 dilution + A431 cell lysate.Predicted band size : 180 kDa.Observed band size : 150 kDa .
FC Image
Flow Cytometry - Anti-EGFR antibody [E234]; Flow cytometric analysis of A431 cells using anti-EGFR RabMAb (red) or a rabbit IgG (negative) (green).

 

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