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Anti-EGFR PHOSPHO Antibody Y38
Also for EGFR (NM_005228)
|A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGF receptor was used as immunogen. The antibody only detects EGFR phosphorylated on Tyrosine 1068 of the mature human isoform 1 (corresponding to Y1092 from the precursor|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000; ICC/IF: 1:100 - 1:250; IHC-P: Use at an assay dependent dilution; FC: 1:40; IP: 1:150
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|IgG fraction (Protein A or G Sepharose)
|Does not react with Mouse, Rat
|Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1|
|ERBB; ERBB1; HER1; mENA; PIG61|
|The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]. |
Cytokine-cytokine receptor interaction
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
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Immunohistochemistry (Paraffin-embedded sections) - EGFR (phospho Y1068) antibody [Y38]; Immunohistochemical analysis of the expression of EGF receptor phosphorilated at Tyrosine 1068 in paraffin embedded prostate cancer, using 1/50 ab32430.
Immunocytochemistry/ Immunofluorescence - EGFR (phospho Y1068) antibody [Y38]; Immunofluorescent analysis of the expression of EGF receptor phosphorilated at Tyrosine 1068 in A431 cells, using 1/100 ab32430.