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Anti-DNM1 Antibody EP772Y
Also for DNM1 (NM_001005336)
|A synthetic peptide corresponding to residues on human Dynamin-1 was used as an immunogen. This antibody detects both phosphorylated and unphosphorylated Dynamin-1.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:5000 - 1:20000; IP: 1:50; ICC/IF: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt,IHC-Fr or IHC-P.
|Homo sapiens dynamin 1 (DNM1), transcript variant 2|
Entrez Gene 1759 Human
|This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]. |
|Druggable Genome EndocytosisFc gamma R-mediated phagocytosis|
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Western blot - Dynamin 1 antibody [ID: EP772Y]; Anti-Dynamin 1 antibody [EP772Y] at 1/20000 dilution + 3T3 cell lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 100 kDa.Observed band size : 100 kDa.
Immunocytochemistry - Dynamin 1 antibody [EP772Y]; TA303480 at 1/50 dilution staining Dynamin 1 in PC12 cells by Immunocytochemistry.