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Anti-DNM1 Antibody EP801Y
Also for DNM1 (NM_001005336)
|A synthetic peptide corresponding to residues on the C-terminus of human Dynamin-1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||ICC/IF: 1:50; WB: 1:2000; IHC-P: Use at an assay dependent dilution
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens dynamin 1 (DNM1), transcript variant 2|
Entrez Gene 1759 Human
Entrez Gene 13429 Mouse
Entrez Gene 140694 Rat
|This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]. |
|Druggable Genome EndocytosisFc gamma R-mediated phagocytosis|
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Western blot - Dynamin 1 antibody [EP801Y]; Anti-Dynamin 1 antibody [EP801Y] at 1/2000 dilution + 3T3 cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP antibody at 1/2000 dilution.Predicted band size : 97 kDa.Observed band size : 97 kDa.
Immunohistochemistry (Paraffin-embedded sections) - Dynamin 1 antibody [EP801Y]; Ab52611 at 1/100-1/250 dilution staining human brain tissue; paraffin embedded.