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Anti-ATF2 Antibody E242
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Also for ATF2 (NM_001880)
|A synthetic peptide corresponding to residues N-terminus of human ATF-2 was used as immunogen. The antibody does not cross-react with other ATF family members. Predicted to cross-react with mouse and rat, based on sequence homology.|
||WB: 1:10,000; IHC: 1:100; ICC: 1:250-1:500; IP: 1:50
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens activating transcription factor 2 (ATF2), transcript variant 1|
|CRE-BP1; CREB2; HB16; TREB7|
|This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq]. |
MAPK signaling pathway
TGF Beta Signaling Pathway
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Western blot analysis on HeLa cell lysate using anti-ATF-2 RabMAb (TA303459); dilution 1:10,000.
Immunohistochemical analysis of paraffin-embedded human carcinoma using anti-ATF-2 RabMAb (TA303459).