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Anti-CDK2 PHOSPHO Antibody EPR2233Y
Also for CDK2 (NM_001798)
|A synthetic phospho-peptide corresponding to residues surrounding tyrosine 15 of human Cdk2 was used as immunogen. The antibody detects Cdk2 phosphorylated on tyrosine 15.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:50
|Does not react with Rat. Is unsuitable for Flow Cyt or IHC-P.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 1|
|The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq]. |
Delta-Notch Signaling Pathway
TGF Beta Signaling Pathway
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Western blot - Cdk2 (phospho Y15) antibody [EPR2233Y]; All lanes : Anti-Cdk2 (phospho Y15) antibody [EPR2233Y] at 1/50000 dilution.Lane 1 : HeLa cell lysates treated with LP.Lane 2 : HeLa cell lysates untreated.Lysates/proteins at 10 µg per lane.Predicted band size : 34 kDa.Observed band size : 33 kDa .