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Home Antibody All anti-CDC2 antibodies

Anti-CDC2 Antibody E53

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303432
  • Rabbit monoclonal antibody against Cdc2 (E53)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400676) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for CDC2 (NM_001786)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues of human Cdc2 was used as immunogen. Predicted to cross-react with most species, based on sequence homology.
Clone NameE53 IsotypeRabbit IgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:5,000; IP: 1:40
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens cyclin-dependent kinase 1 (CDK1), transcript variant 1
Alternative NameCDC2; CDC28A; P34CDC2
Database LinkNP_001777
FunctionThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
Related Pathway
Cell cycle
Hedgehog signaling pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot - Cdc2 antibody [E53]; Anti-CDK1 antibody [E53] at 1/5000 dilution + Hela cell lysate.Predicted band size : 34 kDa.Observed band size : 35 kDa .

 

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