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Anti-CDC2 Antibody E53
Also for CDC2 (NM_001786)
|A synthetic peptide corresponding to residues of human Cdc2 was used as immunogen. Predicted to cross-react with most species, based on sequence homology.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:5,000; IP: 1:40
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens cyclin-dependent kinase 1 (CDK1), transcript variant 1|
|CDC2; CDC28A; P34CDC2|
Entrez Gene 983 Human
|The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]. |
|Protein KinaseStem cell - PluripotencyDruggable Genome Cell cycleOocyte meiosisp53 signaling pathwayGap junctionProgesterone-mediated oocyte maturation|
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Western blot - Cdc2 antibody [E53]; Anti-CDK1 antibody [E53] at 1/5000 dilution + Hela cell lysate.Predicted band size : 34 kDa.Observed band size : 35 kDa .