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Anti-CASP9 Antibody E84
Also for CASP9 (NM_032996)
|A synthetic peptide corresponding to residues near N-terminus of human Caspase-9 was used as immunogen. This antibody only recognises the Pro form of Caspase-9 (46kDa).|
||Protein A purified
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:2000; FC: 1:50; IHC-P: 1:25
|Does not react with Mouse, Rat. Is unsuitable for ICC or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for ICC or IP.
|Homo sapiens caspase 9, apoptosis-related cysteine peptidase (CASP9), transcript variant 3|
|APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56|
|This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq]. |
EGFR1 Signaling Pathway
MAPK signaling pathway
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Western blot - pro Caspase 9 antibody [E84]; Anti-pro Caspase 9 antibody [E84] at 1/2000 dilution + Jurkat cell lysate at 10 µg.Predicted band size : 46 kDa.Observed band size : 46 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-pro Caspase 9 antibody [E84]; Immunohistochemical analysis of paraffin-embedded human colon adenocarcinoma using anti-Pro-Caspase-9 RabMAb.