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Anti-CASP7 Antibody E22
Also for CASP7 (NM_033339)
|A synthetic peptide corresponding to residues near N-terminus of human Caspase-7 was used as immunogen. The antibody should recognize both pro-form and p20 cleaved-form. The antibody does not cross-react with other Caspase family members.|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
||WB: 1:500; IHC: 1:501:100; ICC: 1:100; IP: 1:10
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Mouse, Rat
|Homo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant c|
|CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3|
|This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq]. |
MAPK signaling pathway
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Western blot - Caspase 7 antibody [E22]; Anti-Caspase 7 antibody [E22] at 1/1000 dilution + Jurkat cell lysate.Predicted band size : 34 kDa.Observed band size : 34 kDa.
Immunohistochemistry (Paraffin-embedded sections) - Caspase 7 antibody [E22]; Immunohistochemical analysis of paraffin embedded human skin cancer tissue using ab32522 at 1/50 dilution.
Immunocytochemistry/ Immunofluorescence - Caspase 7 antibody [E22]; Immunofluorescent staining of HeLa cells using ab32522 at 1/100 dilution.