OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-CASP2 antibodies

Anti-CASP2 Antibody Y154

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303416
  • Rabbit monoclonal antibody against Caspase-2(Y154)
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
spacer
Also for CASP2 (NM_032982)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to C-terminus of human Caspase-2 p18 subunit was used as immunogen. The antibody should recognize both pro-form (~50kDa) and p18 cleaved-form of Caspase-2. Predicted to detect the splice isoform (35 kDa) based on sequence
Clone NameY154 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500; IP: 1:20
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens caspase 2, apoptosis-related cysteine peptidase (CASP2), transcript variant 1
Alternative NameCASP-2; ICH1; NEDD-2; NEDD2; PPP1R57
Database LinkNP_116764
FunctionThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq].
Related Pathway
Apoptosis
MAPK signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Caspase 2 antibody [Y154]; Anti-Caspase 2 antibody [Y154] at 1/500 dilution + Jurkat cell lysate.Predicted band size : 49 kDa.Observed band size : 50 kDa .Additional bands at : 18 kDa (possible cleavage fragment).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title