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Home Antibody All anti-CALD1 antibodies

Anti-CALD1 PHOSPHO Antibody EPR2210

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303413
  • Rabbit monoclonal antibody against Caldesmon Phospho (pT730) (EPR2210 ) (phospho-specific)
100ul $325 3-7 Days
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WB(1)
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Also for CALD1 (NM_033157)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho-specific peptide corresponding to residues surrounding Threonine 730 of human Caldesmon was used as an immunogen. The antibody only detects Caldesmon phosphorylated on Threonine 730.
Clone NameEPR2210 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IHC-P.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens caldesmon 1 (CALD1), transcript variant 3
Alternative NameCDM; H-CAD; HCAD; L-CAD; LCAD; NAG22
Database LinkNP_149347
FunctionThis gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
Related Pathway

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WB Image
Western blot - Caldesmon (phospho T730) antibody [EPR2210]; All lanes : Anti-Caldesmon (phospho T730) antibody [EPR2210] at 1/10000 dilution.Lane 1 : HeLa cell lysate, untreated.Lane 2 : HeLa cell lysate, treated with Calyculin A.Lysates/proteins at 10 µg per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 93 kDa.Observed band size : 75 kDa .

 

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