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Anti-C1QB Antibody EPR2982

WB(1)

Gene Name Homo sapiens complement component 1, q subcomponent, B chain (C1QB) Synonyms: OTTHUMP00000002940; complement component 1, q subcomponent, beta polypeptide; complement component C1q, B chain; complement subcomponent C1q chain B; complement component 1, q subcomponent, B chain Immunogen A synthetic peptide corresponding to residues on human C1q (subunit B) was used as an immunogen. Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Clone Name EPR2982 Isotype Rabbit IgG Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB Suggested Dilutions WB: 1:500 -1000; ICC: 1:100 -250 Background This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q. Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of complement component 1, q subcomponent, B chain (C1QB) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • C1QB - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • C1QB - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • C1qb - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • C1QB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • C1qb - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens complement component 1, q subcomponent, B chain (C1QB) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens complement component 1, q subcomponent, B chain (C1QB) as transfection-ready DNA Related cDNA Clones • Homo sapiens complement component 1, q subcomponent, B chain (C1QB) as transfection-ready DNA • Homo sapiens complement component 1, q subcomponent, B chain (C1QB) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)