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Anti-BTK PHOSPHO Antibody EP267Y
|A synthetic phospho-peptide corresponding to residues surrounding Tyrosine 551 of human Btk was used as immunogen. The antibody will detect Btk phosphorylation on Tyrosine 551.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:2,000; ICC: 1:100-250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Mouse, Rat
|Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK), transcript variant 1|
|AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA|
|The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq]. |
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Western blot - BTK (phospho Y551) antibody [EP267Y]; All lanes : Anti-BTK (phospho Y551) antibody [EP267Y] at 1/2000 dilution.Lane 1 : K562 cell lysate non-treated.Lane 2 : K562 cell lysate + Pervanadate.Lane 3 : Jurkat cell lysate non-treated.Lane 4 : Jurkat cell lysate + Pervanadate.Predicted band size : 74 kDa.Observed band size : 74 kDa.