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Home All anti-BCR antibodies
Anti-BCR Phospho Antibody EPR576(2)Y
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
OriGene Data
| A synthetic peptide corresponding to residues surrounding tyrosine 177 of human Bcr was used as immunogen. |
| EPR576(2)Y |
Rabbit IgG |
| Human |
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| WB |
WB: 1:1,000 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens breakpoint cluster region (BCR), transcript variant 1 |
| ALL; BCR1; CML; D22S11; D22S662; PHL |
| NP_004318 |
| A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
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* Shipping is in business days
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WB Image
Western blot analysis on 3T3 cell lysates using anti-phospho Bcr (pY177) RabMAb (TA303404), 1:2000 dilution. The membrane was either (A) untreated (B) treated with pervanadate.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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