OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BCR antibodies

Anti-BCR PHOSPHO Antibody EPR576(2)Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303404
  • Rabbit monoclonal antibody against Bcr Phospho (pY177) (EPR576(2)Y ) (Phospho-Specific)
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding tyrosine 177 of human Bcr was used as immunogen.
Clone NameEPR576(2)Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens breakpoint cluster region (BCR), transcript variant 1
Alternative NameALL; BCR1; CML; D22S11; D22S662; PHL
Database LinkNP_004318
FunctionA reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Bcr (phospho Y177) antibody [EPR576(2)Y]; All lanes : Anti-Bcr (phospho Y177) antibody [EPR576(2)Y] at 1/1000 dilution.Lane 1 : 3T3 cell lysate, membrane un-treated.Lane 2 : 3T3 cell lysate, membrane treated with pervanadate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 143 kDa.Observed band size : 153 kDa .

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title