Home Antibody All anti-AVPR1B antibodies
Also for AVPR1B (NM_000707)
| Peptide with sequence C-PRDLELADGEGTAE, from the C-Terminus of the protein sequence according to NP_000698.1.|
|Test: Human. Expected from seq similarity: Human
||ELISA: 1:32,000. WB: 0.05-0.2µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens arginine vasopressin receptor 1B (AVPR1B)|
Entrez Gene 553 Human
|The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq]. |
|GPCRTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionVascular smooth muscle contraction|
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EB08785 (0.5µg/ml) staining of Human Amygdala lysate (35µg protein in RIPA buffer) in lane A . Primary incubation was 1 hour. Detected by chemiluminescence.