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Home Antibody All anti-HCRTR1 antibodies

Anti-HCRTR1 Antibody


Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Goat Polyclonal Antibody against HCRTR1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400584) , 20ug Explanation
100ug $325 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart


OriGene Data

Immunogen Peptide with sequence C-YNFLSGKFREQFK, from the internal region of the protein sequence according to NP_001516.1; NP_001517.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsELISA: 1:32,000. WB: 0.3-1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens hypocretin (orexin) receptor 1 (HCRTR1)
Alternative NameOX1R
Database LinkNP_001516
Entrez Gene 3061 Human
Entrez Gene 230777 Mouse
Entrez Gene 25593 Rat
Entrez Gene 100855896 Dog
FunctionThe protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq].
Related PathwayGPCRES Cell Differentiation/IPSTransmembraneDruggable Genome Neuroactive ligand-receptor interaction

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TA303362 (0.5µg/ml) staining of Frontal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Figure from citation: Western Blot of HCRTR1 protein level by using anti-HCRTR1 antibody in mouse membrane fractions. Dilution: 1:500 View Citation
Figure from citation: Immunocytochemical analysis of HCRTR-1 expression by using anti-HCRTR1 antibody. In layer V of SS (C), the HCRTR-1 granular immunoreactivity was mainly detected at the level of neuronal cell bodies sometimes clearly identifiable as pyramidal neurons, based on morphology (arrows). (C') gives a higher magnification detail of (C). In layer V of Fr2 (D), the HCRTR-1 positive (+) signal was considerably more intense than in SS and was detectable not only in numerous cell bodies (arrows and inset in D'), but also in neuropilar processes of different caliber (arrowheads). (D') gives a higher magnification detail of (C). Scale bars: 50 µm (C, D); 30 µm (C'); 20 µm (D'). Dilution: 1:150 View Citation


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