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Home Antibody All anti-HCRTR1 antibodies

Anti-HCRTR1 Antibody


Specifications Citations (1) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303362 Goat Polyclonal Antibody against HCRTR1 100ug $325 2 Weeks
LC400584 HCRTR1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenPeptide with sequence C-YNFLSGKFREQFK, from the internal region of the protein sequence according to NP_001516.1; NP_001517.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsELISA: 1:32,000. WB: 0.3-1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens hypocretin receptor 1 (HCRTR1)
Alternative NameOX1R
Database LinkNP_001516
Entrez Gene 3061 Human
Entrez Gene 230777 Mouse
Entrez Gene 25593 Rat
Entrez Gene 100855896 Dog
FunctionThe protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq].
Related PathwayGPCRES Cell Differentiation/IPSTransmembraneDruggable Genome Neuroactive ligand-receptor interaction

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303362 (0.5µg/ml) staining of Frontal Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

WB Image
Figure from citation: Western Blot of HCRTR1 protein level by using anti-HCRTR1 antibody in mouse membrane fractions. Dilution: 1:500 View Citation

IF Image
ICC analysis of HCRTR-1 expression by using anti-HCRTR1 antibody. In layer V of SS (C), the HCRTR-1 granular immunoreactivity was detected at the level of neuronal cell bodies based on morphology (arrows). (C') gives a higher magnification detail of (C). In layer V of Fr2 (D), the HCRTR-1 positive (+) signal was more intense than in SS(arrows and inset in D'), but also in neuropilar processes of different caliber (arrowheads). (D') gives a higher magnification detail of (C). Dilution: 1:150


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