Homo sapiens adrenergic, beta-3-, receptor (ADRB3)
Synonyms:
BETA3AR; FLJ99960
Immunogen
Peptide with sequence PHENSSLAPWPD-C, from the N Terminus of the protein sequence according to NP_000016.1.
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clone Name
Isotype
Goat IgG
Species Reactivity
Human
Concentration
0.5 mg/ml
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Guaranteed Application *
WB
Suggested Dilutions
Peptide ELISA: antibody detection limit dilution 1:128,000. Western blot recommended concentration: 0.03-0.1µg/ml.
Background
The ADRB3 gene product, beta-3-adrenergic receptor, is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epenephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. [provided by RefSeq].
Related Pathway
Signaling by GPCR
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TA303277 (0.03µg/ml) staining of Human Brain (Cerebral Cortex) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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