Home Antibody All anti-IGFBP3 antibodies
Also for IGFBP3 (NM_000598)
| Peptide with sequence C-RYKVDYESQSTDTQN, from the internal region of the protein sequence according to NP_001013416.1; NP_000589.2.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog
||Lot dependent; please refer to CoA along with shipment
||ELISA: 1:64,000. WB: 0.02-0.06µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2|
Entrez Gene 3486 Human
Entrez Gene 16009 Mouse
Entrez Gene 24484 Rat
Entrez Gene 100855619 Dog
|This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]. |
|Secreted ProteinDruggable Genome p53 signaling pathway|
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TA303275 (0.02µg/ml) staining of Human Breast cancer lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.