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Home Antibody All anti-PCK1 antibodies

Anti-PCK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303224
  • Goat Polyclonal Antibody against PCK1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419231) , 20ug Explanation
100ug 325 In Stock
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WB(1)
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Also for PCK1 (NM_002591)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-EKEVEDIEKYLEDQ, from the internal region (near the C Terminus) of the protein sequence according to NP_002582.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 0.5-1.5µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens phosphoenolpyruvate carboxykinase 1 (soluble) (PCK1)
Alternative NamePEPCK-C; PEPCK1; PEPCKC
Database LinkNP_002582
Entrez Gene 5105 Human
FunctionThis gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq].
Related PathwayDruggable Genome Glycolysis / GluconeogenesisCitrate cycle (TCA cycle)Pyruvate metabolismMetabolic pathwaysPPAR signaling pathwayInsulin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303224 (0.5µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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