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Home Antibody All anti-AIRE antibodies

Anti-AIRE Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303185
  • Goat Polyclonal Antibody against AIRE (Internal Region)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424752) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for AIRE (NM_000383)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-KAKPPKKPESSAEQ, from the internal region of the protein sequence according to NP_000374.1; NP_000649.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:64,000. WB: 0.3-1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens autoimmune regulator (AIRE)
Alternative NameAIRE1; APECED; APS1; APSI; PGA1
Database LinkNP_000374
FunctionThis gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). [provided by RefSeq].
Related Pathway

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WB Image
TA303185 (0.3µg/ml) staining of human spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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