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Home Antibody All anti-PARK2 antibodies

Anti-PARK2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303148
  • Goat Polyclonal Antibody against PARK2
100ug $325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-DERAAEQARWEAASKE, from the internal region of the protein sequence according to NP_004553.1; NP_054642.1; NP_054643.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:128,000. WB: 0.1-0.3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens parkin RBR E3 ubiquitin protein ligase (PARK2), transcript variant 1
Alternative NameAR-JP; LPRS2; PDJ; PRKN
Database LinkNP_004553
FunctionThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq].
Related Pathway

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WB Image
TA303148 (0.1µg/ml) staining of Human Brain (frontal cortex) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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